Flowchart of the Rosetta Stone end-to-end framework: scheme of the comparison between observations and simulations by means of the production of realistic synthetic observations. Real data and inherent information are highlighted in green, synthetic data (RMHD simulations, radiative transfer, synthetic observations) in purple, and the steps of the analysis performed on both real and synthetic maps in orange. In the lighter-shaded boxes we specify how the building blocks of the Rosetta Stone framework have been adapted in this work for the SQUALO project (Traficante et al. 2023) science case.