Simulated H₂O detectability map for GJ 436 b produced with EXoPLORE assuming a single transit observed with ANDES. The white and red contours indicate recovered S/N levels of 10 and 5 with in-silico data, respectively. To illustrate the improvement over current constraints, we show the S/N = 5 contour (orange curve) derived from combining the CARMENES and CRIRES⁺ data (Fig. 8). Although based on simulations, the map illustrates the significant improvement in sensitivity that ANDES and the ELT are expected to provide for probing cloudy sub-Neptune atmospheres.