Skeletons extracted with getsf, FilFinder and DisPerSE. a) Skeletons extracted with getsf ; b) Skeletons extracted with FilFinder; c) Skeletons extracted with DisPerSE. Three algorithms show similar extraction results. However, the three algorithms still show clear differences in details. At high-density regions with prominent filaments (red dashed box), getsf identifies a well-defined skeleton, whereas FilFinder and DisPerSE tend to produce two many closed loops. In low-density areas (blue dashed box), getsf again extracts a complete filament skeleton, while FilFinder and DisPerSE can only deliver a small portion of the filament. Thus, although all three algorithms deliver broadly similar results, getsf behaves better than the other two.