Comparison of D-COM and COM abundances normalized to methanol for IRAS 16293E and the nearby protostars A and B from ALMA Band 7 PILS data (Jørgensen et al. 2018; Calcutt et al. 2018; Manigand et al. 2020; Drozdovskaya et al. 2022), as well as from Nazari et al. (2024), who observed IRAS 16293B in ALMA Band 3 (overlaid dotted pattern). The upper limits for CH₂CHCN are bins with downward arrows that have an overlaid hatching pattern (note: not shown is the IRAS 16293B Band 3 upper limit for CH₂CHCN, which is <4.9 × 10⁻⁴). The methanol column density for IRAS 16293B (Band 7) stems from the analysis of the optically thin ¹⁸O-isotopologue of methanol and subsequent assumption of the canonical ¹⁶O/¹⁸O ISM ratio (Jørgensen et al. 2018), while that for IRAS 16293A is based on the analysis of selected optically thin lines of the main isotopologue itself (Manigand et al. 2020).